BioAcyl Corp
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Lacy, B. E. (2016). Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome. International Journal of General Medicine, 9, 7–17. Added by: Dr. Enrique Feoli (15/06/2023, 19:01) Last edited by: Dr. Enrique Feoli (15/06/2023, 19:02) |
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| Resource type: Journal Article DOI: 10.2147/IJGM.S93698 ID no. (ISBN etc.): 1178-7074 BibTeX citation key: Lacy2016 View all bibliographic details  |
Categories: BioAcyl Corp Subcategories: Irritable Bowel Creators: Lacy Collection: International Journal of General Medicine |
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| Abstract |
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Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders worldwide. The economic impact of IBS on the health care system is substantial, as is the personal impact on patients. Patients with diarrhea-predominant IBS (IBS-D) comprise a substantial proportion of the overall IBS population. Primary care providers are often the first point of contact for patients with IBS-D and can accurately diagnose IBS after a careful history and examination without extensive diagnostic tests. Several pharmacologic treatments (eg, loperamide, alosetron, and antidepressants) and non-pharmacologic treatments (eg, dietary modification and probiotics) are available for IBS-D, but restrictions on use (eg, alosetron) or the lack of controlled trial data showing reductions in both global and individual IBS-D symptoms (eg, bloating, pain and stool frequency) emphasize the need for alternative treatment options. Two newer medications (eluxadoline and rifaximin) were approved in May 2015 for the treatment of IBS-D, and represent new treatment options for this common gastrointestinal condition.
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